Polyamine homeostasis in arginase knockout mice

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Polyamine homeostasis in arginase knockout mice.

The role of ornithine decarboxylase (ODC) in polyamine metabolism has long been established, but the exact source of ornithine has always been unclear. The arginase enzymes are capable of producing ornithine for the production of polyamines and may hold important regulatory functions in the maintenance of this pathway. Utilizing our unique set of arginase single and double knockout mice, we ana...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Cell Physiology

سال: 2007

ISSN: 0363-6143,1522-1563

DOI: 10.1152/ajpcell.00393.2006